Product datasheet
Anti-SENP2 antibody ab3660
1 References 2 Images
Overview
Product name
Anti-SENP2 antibody
Description
Rabbit polyclonal to SENP2
Tested applications
WB, ELISA, IHC-P
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat
Immunogen
Synthetic peptide:
KTKRNSDLNLLEWTHHS
, corresponding to amino acids 517-533 of Human SENP 2.
Run BLAST with
Positive control
Run BLAST with
HL60 whole cell lysate.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or 80°C. Avoid freeze / thaw cycle.
Storage buffer
PBS with 0.1% sodium azide
Purity
Protein G purified
Purification notes
This antibody is purified through a protein G column and eluted out with both high and low pH
buffers. It is neutralized immediately after elution, followed by dialysis against PBS.
Clonality
Polyclonal
Isotype
IgG
Applications
Our Abpromise guarantee covers the use of ab3660 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application
Abreviews
Notes
WB
ELISA
1
Application
Abreviews
Notes
IHC-P
Application notes
ELISA: 1/1000.
IHC-P: 1/50 - 1/100.
WB: 1/100 - 1/500.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Expected molecular weight: 67.952 kDa (SwissProt Q9HC62).
Target
Function
Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length
SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and
SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the
Wnt pathway.
Sequence similarities
Belongs to the peptidase C48 family.
Domain
The N-terminus is necessary and sufficient for nuclear envelope targeting.
Post-translational
modifications
Polyubiquitinated; which leads to proteasomal degradation.
Cellular localization
Nucleus > nuclear pore complex. Nucleus membrane. Cytoplasm. Shuttles between cytoplasm
and nucleus.
Anti-SENP2 antibody images
ab3660 at a 1/100 dilution staining
approximately 68 kDa band of SENP2 in
Jurkat cell lysate by Western blot (ECL).
Western blot - SENP2 antibody (ab3660)
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ab3660 staining SENP2 in human breast
carcinoma (BC) tissue by
Immunohistochemistry (Formalin/PFA-fixed
paraffin-embedded sections).
Immunohistochemistry (Formalin/PFA-fixed
paraffin-embedded sections) - SENP2 antibody
(ab3660)
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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Terms and conditions
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