Seeks partner to license
Label-free surface wave sensor for analysis of biomolecular interactions
This portable sensing device can analyze static binding in microarrays to a sensitivity of ~1.5 µ g/mL (4pg per 265 µ m spot) using a technology similar to that used in surface plasmon resonance sensors, but without the requirement for metal films or a flow configuration.
The multilayer sample platform is the size of a microscope slide, can be inexpensively mass-produced, and can be custom-prepared using any commercial microarrayer.
Exposure to a (multi)analyte solution, followed by rinsing and automatic 3-D scanning, is all that is required to get an image like the one above. The device is easy to use, suitable for research, and potentially for clinical applications.
Applications: Research and Commercial
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DNA binding Clinical
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Protein/Antibody immunosensing
Kinetics
Forensic/Homeland Security
Food Safety
Environmental
Advantages
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Increased sensitivity
Decreased background interference
Detect trace amount of biological and chemical entities
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Label-free
No fluorescent or radioactive labels
Decreased cross-reactivity
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Less expensive
Inexpensive disposable sample substrate
A dry, pre-prepared array can be stored until needed
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Versatile design
Tailored to your size range and sensitivity needs
Microarray-based sample prep
The Inventor
Dr. William Robertson is a Professor of Physics at Middle Tennessee State University. He earned his doctoral degree from Purdue University and has twenty years of experience in the area of surface EM waves and optics in academics, industry, and government laboratories.
Dr. Robertson works closely with an interdisciplinary group of biologists and chemists to develop this device and its applications.
For more information on licensing contact:
Middle Tennessee State University
Office of Intellectual Property and Commercialization
615-898-5005 email: research@mtsu.edu