List of publications directly emanating from the project
Refereed papers only. Abstracts are not included
1
Allen NJ, Attwell D (2004) The effect of simulated ischaemia on spontaneous GABA
release in area CA1 of the juvenile rat hippocampus. J Physiol 561:485-498
2
Allen NJ, Karadottir R, Attwell D (2004) Reversal or reduction of glutamate and GABA
transport in CNS pathology and therapy. Pflugers Arch 449:132-142
3
Allen NJ, Karadottir R, Attwell D (2005) A preferential role for glycolysis in preventing
the anoxic depolarization of rat hippocampal area CA1 pyramidal cells. J Neurosci
25:848-859.
4
Allen NJ, Rossi DJ, Attwell D (2004) Sequential release of GABA by exocytosis and
reversed uptake leads to neuronal swelling in simulated ischemia of hippocampal slices. J
Neurosci 24:3837-3849
5
Attwell D, Iadecola C (2002) The neural basis of functional brain imaging signals. Trends
Neurosci 25:621-625
6
Bergersen L, Ruiz A, Bjaalie JG, Kullmann DM, Gundersen V (2003) GABA and
GABAA receptors at hippocampal mossy fibre synapses. Eur J Neurosci 18:931-941
[Joint publication #1 & #3]
7
Bezzi P, Gravaghi C, Grohovaz F, Volterra A (2006) Prostaglandins mediate a component
of astrocyte calcium elevations responsible for receptor-stimulated glutamate release. In
preparation [Joint publication #4 & #5]
8
Bezzi P*, Gundersen V*, Galbete JL, Seifert G, Steinhauser C, Pilati E, Volterra A (2004)
Astrocytes contain a vesicular compartment that is competent for regulated exocytosis of
glutamate. Nat Neurosci 7:613-620 *These authors contributed equally
[Joint publication #1 & #4]
9
Billups D, Attwell D (2003) Active release of glycine or D-serine saturates the glycine site
of NMDA receptors at the cerebellar mossy fibre to granule cell synapse. Eur J Neurosci
18:2975-2980
10 Boulland JL, Qureshi T, Seal RP, Rafiki A, Gundersen V, Bergersen LH, Fremeau RT,
Jr., Edwards RH, Storm-Mathisen J, Chaudhry FA (2004) Expression of the vesicular
glutamate transporters during development indicates the widespread corelease of multiple
neurotransmitters. J Comp Neurol 480:264-280
11 Cavelier P, Attwell D (2005) Tonic release of glutamate by a DIDS-sensitive mechanism
in rat hippocampal slices. J Physiol 564:397-410
12 Cavelier P, Hamann M, Rossi D, Mobbs P, Attwell D (2005) Tonic excitation and
inhibition of neurons: ambient transmitter sources and computational consequences. Prog
Biophys Mol Biol 87:3-16
1
13 Chiulli N, Codazzi F, Di Cesare A, Gravaghi C, Zacchetti D, Grohovaz F (2006) Effect of
sphingosylphosphocholine on astrocytes: a possible mechanism mediating neurotoxicity
in Niemann-Pick type A disease. Submitted
14 Codazzi F, Di Cesare A, Chiulli N, Albanese A, Meyer T, Zacchetti D, Grohovaz F
(2006) Synergistic control of protein kinase Cgamma activity by ionotropic and
metabotropic glutamate receptor inputs in hippocampal neurons. J Neurosci 26(13):340411
15 De Pietri Tonelli D, Mihailovich M, Di Cesare A, Codazzi F, Grohovaz F, Zacchetti D
(2004) Translational regulation of BACE-1 expression in neuronal and non-neuronal cells.
Nucleic Acids Res 32:1808-1817
16 Di Cesare A, Del Piccolo P, Codazzi F, Zacchetti D, Grohovaz F (2006) EP2 receptor
promotes calcium responses in astrocytes via activation of the adenylate cyclase pathway.
In preparation
17 Domercq M, Pietropoli A, Jourdain P, Brambilla L, Pilati E, Kollias G, Matute C, Bezzi P
and Volterra A. (2006) An astrocyte control of excitatory transmission in hippocampus
via purinoreceptors. Submitted
18 Evanko DS, Zhang Q, Zorec R, Haydon PG (2004) Defining pathways of loss and
secretion of chemical messengers from astrocytes. Glia 47:233-240
19 Fremeau RT Jr, Burman J, Qureshi T, Tran CH, Proctor J, Johnson J, Zhang H, Sulzer D,
Copenhagen DR, Storm-Mathisen J, Reimer RJ, Chaudhry FA, Edwards RH (2002) The
identification of vesicular glutamate transporter 3 suggests novel modes of signaling by
glutamate. Proc Natl Acad Sci USA 99:14488-14493
20 Fremeau RT Jr, Kam K, Qureshi T, Johnson J, Copenhagen DR, Storm-Mathisen J,
Chaudhry FA, Nicoll RA, Edwards RH (2004) Vesicular glutamate transporters 1 and 2
target to functionally distinct synaptic release sites. Science 304(5678):1815-1819
21 Furness DN, Dehnes Y, Qureshi A, Rossi D, Hamann M, Grutle N, Gundersen V,
Holmseth S, Lehre KP, Ullensvang K, Attwell D, Danbolt NC (2006) A quantitative
assessment of glutamate uptake into hippocampal synaptic terminals and astrocytes. In
preparation [Joint publication #1 & #2]
22 Gammelsaeter R, Frøyland M, Aragón C, Danbolt NC, Fortin D, Storm-Mathisen J,
Davanger S, Gundersen V (2004) Glycine, GABA and their transporters in pancreatic
neuroendocrine cells: evidence for a transmitter paracrine interplay. J Cell Sci 117(Pt
17):3749-3758.
23 Gundersen V, Holten AT, Storm-Mathisen J (2004) GABAergic synapses in hippocampus
exocytose aspartate on to NMDA receptors: quantitative immunogold evidence for cotransmission. Mol Cell Neurosci 26:156-165.
24 Hamann M, Rossi DJ, Mohr C, Andrade AL, Attwell D (2005) The electrical response of
cerebellar Purkinje neurons to simulated ischaemia. Brain 128:2408-2420.
2
25 Holmseth S, Dehnes Y, Bjornsen LP, Boulland JL, Furness DN, Bergles D, Danbolt NC
(2005) Specificity of antibodies: unexpected cross-reactivity of antibodies directed against
the excitatory amino acid transporter 3 (EAAT3). Neuroscience 136: 649-660.
26 Holmseth S, Dehnes Y, Furness DN, Plachez C, Bjornsen LP, Mylonakou NM, Bergles D,
Danbolt NC, Lehre KP (2006) The concentration of the excitatory amino acid transporter
3 protein (EAAT3) in young adult Wistar rat hippocampus is 100-fold lower than that of
EAAT2. In preparation
27 Holmseth S, Lehre KP, Danbolt NC (2006) Specificity controls for
immunocytochemistry. Anat Embryol (Berl) Jan 25;:1-10 [Epub ahead of print 2006 Jan
25]
28 Holmseth S, Martin VV, Lehre KP, Bergles D, Danbolt NC (2006) Specificity controls for
immunocytochemistry: Pre-absorbing antibodies with the antigen does not test whether
the antibodies bind to the same antigen in tissue sections. In preparation
29 Jourdain P*, Bergersen LH*, Bhaukaurally K, Bezzi P, Domercq M, Matute C, Tonello F,
Gundersen V, Volterra A (2006) Glutamate exocytosis from astrocytes controls synaptic
strength. Submitted *These authors contributed equally [Joint publication #1 & #4]
30 Káradóttir R, Cavelier P, Bergersen LH, Attwell D (2005) NMDA receptors are expressed
in oligodendrocytes and activated in ischemia. Nature 438:1162-1166
[Joint publication #1 & #3]
31 Kreft M, Krizaj D, Grilc S, Zorec R (2003) Properties of exocytotic response in vertebrate
photoreceptors. J Neurophysiol 90:218-225
32 Kreft M, Milisav I, Potokar M, Zorec R (2004) Automated high through-put
colocalization analysis of multichannel confocal images. Comput Methods Programs
Biomed 74:63-67
33 Kreft M, Stenovec M, Rupnik M, Grilc S, Krzan M, Potokar M, Pangrsic T, Haydon PG,
Zorec R (2004) Properties of Ca(2+)-dependent exocytosis in cultured astrocytes. Glia
46:437-445
34 Krzan M, Stenovec M, Kreft M, Pangrsic T, Grilc S, Haydon PG, Zorec R (2003)
Calcium-dependent exocytosis of atrial natriuretic peptide from astrocytes. J Neurosci
23:1580-1583
35 Lehre KP, Rusakov DA (2002) Asymmetry of glia near central synapses favors
presynaptically directed glutamate escape. Biophys J 83:125-134
[Joint publication #1 & #3]
36 Marcaggi P, Attwell D (2004) Role of glial amino acid transporters in synaptic
transmission and brain energetics. Glia 47:217-225
37 Marcaggi P, Attwell D (2005) Endocannabinoid signaling depends on the spatial pattern
of synapse activation. Nat Neurosci 8:776-781
3
38 Marcaggi P, Billups D, Attwell D (2003) The role of glial glutamate transporters in
maintaining the independent operation of juvenile mouse cerebellar parallel fibre
synapses. J Physiol 552:89-107.
39 Marie H, Billups D, Bedford FK, Dumoulin A, Goyal RK, Longmore GD, Moss SJ,
Attwell D (2002) The amino terminus of the glial glutamate transporter GLT-1 interacts
with the LIM protein Ajuba. Mol Cell Neurosci 19:152-164
40 Marie H, Pratt SJ, Betson M, Epple H, Kittler JT, Meek L, Moss SJ, Troyanovsky S,
Attwell D, Longmore GD, Braga VM (2003) The LIM protein Ajuba is recruited to
cadherin-dependent cell junctions through an association with alpha-catenin. J Biol Chem
278:1220-1228
41 Micheletti M, Brioschi A, Fesce R, Grohovaz F (2005) A novel pattern of fast calcium
oscillations points to calcium and electrical activity cross-talk in rat chromaffin cells. Cell
Mol Life Sci 62:95-104
42 Potokar M, Kreft M, Pangrsic T, Zorec R (2005) Vesicle mobility studied in cultured
astrocytes. Biochem Biophys Res Commun Apr 8;329(2):678-83.
43 Renden R, Taschenberger H, Puente N, Rusakov DA, Duvoisin R, Wang LY, Lehre KP,
von Gersdorff H (2005) Glutamate transporter studies reveal the pruning of metabotropic
glutamate receptors and absence of AMPA receptor desensitization at mature calyx of
Held synapses . J Neurosci 25: 8482-8497 [Joint publication #1 & #3]
44 Rusakov DA, Lehre KP (2002) Perisynaptic asymmetry of glia: new insights into
glutamate signalling. Trends Neurosci 25:492-494 [Joint publication #1 & #3]
45 Rusakov DA, Saitow F, Lehre KP, Konishi S (2005) Modulation of presynaptic Ca2+
entry by AMPA receptors at individual GABAergic synapses in the cerebellum. J
Neurosci 25:4930-4940 [Joint publication #1 & #3]
46 Savtchenko LP, Rusakov DA (2005) Extracellular diffusivity determines contribution of
high-versus low-affinity receptors to neural signaling. Neuroimage 25:101-111
47 Scimemi A, Fine A, Kullmann DM, Rusakov DA (2004) NR2B-containing receptors
mediate cross talk among hippocampal synapses. J Neurosci 24:4767-4777
48 Scimemi A, Schorge S, Kullmann DM, Walker MC (2006) Epileptogenesis is associated
with enhanced glutamatergic transmission in the perforant path. J Neurophysiol 95:12131220
49 Stenovec M, Kreft M, Grilc S, Pangršic T, Zorec R (2005) EAAT2 at the astrocyte plasma
membrane and Ca2+ -regulated exocytosis. Submitted
50 Volterra A, Steinhauser C (2004) Glial modulation of synaptic transmission in the
hippocampus. Glia 47:249-257
51 Zhang Q, Pangrsic T, Kreft M, Krzan M, Li N, Sul JY, Halassa M, Van BE, Zorec R,
Haydon PG (2004) Fusion-related release of glutamate from astrocytes. J Biol Chem
279:12724-12733
4