USD 2770
Pall® Minidisc Capsules with Pegasus™
SV4 Virus Removal Filter Membrane
Compact, Easily-scalable Capsules for Virus Removal
and Small-scale Membrane Qualification Studies
Features
Benefits
Fully disposable capsule with Luer connections
Pegasus SV4 virus removal filter membrane
Constant flow and high throughput performance
Identical membrane to larger production
scale Pegasus SV4 virus filter cartridges
Individual capsules identified by lot and serial number
Easy handling, ready to use
Robust, high > 4 LRV parvovirus virus clearance
Maximize virus filter process economy as well as efficiency
Offers reliable scalability
100% manufacturing assembly tested
Membrane bacteriophage tested
Pre- and post-use installation testable
Low protein-binding
Robust membrane with high viral clearance
Easy identification of individual capsules with
complete traceability of manufacturing history
Assurance of consistently high quality
Assurance of consistently high quality
Assurance of consistently high quality at point of use
High protein recovery
Flow decay minimized at high virus spike concentrations
and with complex or concentrated feeds
Description
Retention Ratings
Pegasus SV4 Virus Removal filters combine robust, high viral
clearance of parvovirus and larger viruses with high throughput
capacity and stable flowrates in both dilute and complex,
concentrated biological fluids. Consistent flowrate and throughput performance provide superior control of process costs and
maximize virus filtration economy and efficiency.
Pall Minidisc Capsules with Pegasus SV4 Virus Removal Filter
Membrane are purpose-designed for small-scale membrane
qualification studies such as bacteriophage or prion (TSE agent)
clearance, as well as membrane flow rate, capacity and protein
transmission studies. They are 100% manufacturing tested and
manufactured under a Quality Management System certified to
ISO 9001:2008 in order to assure consistent high quality.
High Quality Standards
Virus
Bacteriophage PP7
* Claims based on challenge with parvovirus model bacteriophage
(bacterial virus) PP7
† > 4 LRV for PP7 bacteriophage per Parenteral Drug Association (PDA)
TR 41 rating method for small virus-retentive filters
> 4 LRV typically with mammalian parvoviruses
Effective Surface Area
9.6 cm2 (1.49 in2)
Operating Parameters1
Maximum Temperature
Maximum Operating Pressure
Maximum Differential Pressure
1
Meets the current USP requirements under Section <85>
Bacterial Endotoxins Test.
Materials
> 4 log TR*†
25°C
3.1 barg (45 psig)
3.1 bard (45 psid)
Temporary pressures up to 3.4 barg (50 psig) are acceptable, but the
target operating and differential pressures should not exceed 3.1 bar
(45 psi) to allow for pressure fluctuations during testing.
Ordering Information
Filter fluid path components have met the specifications
under Section <88> Biological Reactivity Tests in vivo listed in
the current revision of the United States Pharmacopeia (USP)
for Class VI plastics at 121°C.
Pall Minidisc Capsules with Pegasus SV4 Virus
Removal Filter Membrane2
2
Part Number
10MCFSV4
Three capsules per box
Technical Data
Materials of Construction
Item
Membrane
Support Disc
O-ring
Capsule Inlet and Outlet
Material
Hydrophilic modified polyvinylidene fluoride (PVDF)
Polypropylene (Non-woven)
EPDM
Polycarbonate
Pore size
20 nm (nominal)
Further Equipment Recommended for
Laboratory Testing
Pressure Vessels (disposable)
Novasip™ vessel
Part Number
C3EP1
Accessories (Novasip Vessel)
Adapter 1 in. TC/Male Stäubli
connector plug (3 mm) R 1⁄4 in.
TC clamp + silicone gasket
Part Number
GFX0290
SLK1TC23H4
To see how Pall is helping enable a greener, safer and more sustainable
future, visit www.pall.com/green.
Visit us on the Web at www.pall.com/biopharm
E-mail us at biopharm@pall.com
Corporate Headquarters
Port Washington, NY, USA
+1.800.717.7255 toll free (USA)
+1.516.484.5400 phone
biopharm@pall.com e-mail
European Headquarters
Fribourg, Switzerland
+41 (0)26 350 53 00 phone
LifeSciences.EU@pall.com e-mail
Asia-Pacific Headquarters
Singapore
+65 6389 6500 phone
sgcustomerservice@pall.com e-mail
International Offices
Pall Corporation has offices and plants throughout the world in locations such as:
Argentina, Australia, Austria, Belgium, Brazil, Canada, China, France, Germany, India,
Indonesia, Ireland, Italy, Japan, Korea, Malaysia, Mexico, the Netherlands, New Zealand,
Norway, Poland, Puerto Rico, Russia, Singapore, South Africa, Spain, Sweden,
Switzerland, Taiwan, Thailand, the United Kingdom, the United States, and Venezuela.
Distributors in all major industrial areas of the world. To locate the Pall office or distributor
nearest you, visit www.pall.com/contact.
The information provided in this literature was reviewed for accuracy at the time of publication. Product data may be subject to change without notice. For current information
consult your local Pall distributor or contact Pall directly.
© 2012, Pall Corporation. Pall,
, Pegasus and Novasip are trademarks of Pall Corporation.
® indicates a trademark registered in the USA and TM indicates a common law trademark.
ENABLING A GREENER FUTURE and Filtration. Separation. Solution.are service marks of Pall Corporation.
11/12, PDF, GN10.4151
USD 2770