Radiologic Events

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Radiologic Events:
Attack on a Nuclear Power Plant
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Objectives
• Recognize the potential consequences of
a terrorist attack on a nuclear power plant
• Describe the different types of radiation
particles and waves and their effect on the
body
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Objectives
• Differentiate between radiation exposure
and contamination
• Recognize the characteristic signs and
symptoms of acute radiation syndrome
• Learn to perform rapid assessment of
nuclear/radiation events in a disaster
situation
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Objectives
• Learn specific antidotes and medical
interventions for nuclear/radiation
terrorism victims
• Learn specific pre-hospital and hospital
management strategies including proper
notification of radiation disasters
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Case
• Terrorists attack a nuclear power plant 30
miles outside a major metropolitan area by
flying a high jacked jet liner into the plant.
• The impact results in an explosion and fire.
• Fire fighters and paramedics are called
to the scene.
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Case
• There are multiple casualties and
several trauma victims are being
transported to your health care facility.
• The news media is questioning your
health team regarding radiation
exposure risks
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Nuclear Power Plant Disaster:
Chernobyl, 1986
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Attacks on Reactors
• Radioisotopes released
– Large quantities of radioiodines and
radiocesiums
– A large variety of other radioisotopes may
be released in smaller quantities
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Attacks on Reactors
• Which way is the
wind blowing?
– The radioactive cloud
from the burning
reactor will travel
according to wind
direction.
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Attacks on Reactors
• Prevention
– Individuals in the path of
the radioactive cloud need
to be evacuated
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Electromagnetic Radiation
• Electromagnetic
radiation includes a
wide spectrum of
radiation energy
characterized by
frequency and wave
length.
• Ionizing radiation has
high frequency and
short wave length
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Ionizing Radiation
• Ionizing radiation includes both
electromagnetic (X and gamma rays)
and particulate radiation
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Particles
• Alpha
• Beta
• Neutrons
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Alpha Particles
• A helium nucleus
• Unable to penetrate skin
• Emitted from radioisotopes
such a plutonium, uranium
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n
n
++
Beta Particles
• Able to penetrate skin
• Negatively charged
• Can produce skin superficial burns
• Emitted by several radioisotopes (e.g.
Cobalt 160)
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Neutron particles
• Uncharged
• Able to penetrate deeply
• Hazard inside nuclear reactors
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Penetration Abilities of Different
Types of Radiation
Alpha Particles
Stopped by a sheet of paper
Radiation
Source
Beta Particles
Stopped by a layer of clothing
or less than an inch of a substance
(e.g. plastic)
Gamma Rays
Stopped by inches to feet of concrete
or less than an inch of lead
Neutrons
Stopped by a few feet of concrete
X-Rays and Gamma Rays
• Gamma and X radiation differ
by source: gamma rays comes
from the nucleus and X-rays
come from the electron orbits
• Because they don’t have mass
or charge, they penetrate
very deeply
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Detecting Radiation
RADIATION CANNOT BE SEEN,
HEARD, TASTED OR SMELLED
But, it can be easily measured
if you have the right equipment
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Radiation Detectors
Alpha Survey Meter
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Beta and Gamma
Survey Meter
Radiation Dose Units
Unit
Value
Rad (radiation
absorbed dose)
Rem (radiation
equivalent-man)
Gray (Gy)
0.01 J/kg
Sievert (SV)
100 rem
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Bio damage from 0.01 J/kg
100 rad
Contamination
• Contact with radioactive material (radionuclides)
that can be spread to other people / properties
• Inhaled, ingested, transferred from surface to
surface
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Exposure vs. Contamination
External Exposure: external
irradiation of the body with rays or
particles  absorbed dose
Contamination: radioactive material
(radionuclides) on patient (external)
or within patient (internal).
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Adapted from CDC Bioterrorism Web site
If the patient is
externally
contaminated
with radionuclides,
you can
Decontaminate
If radionuclides have
gotten inside the body,
consider chelation
therapy
Factors Determining
Radiation Exposure
• Time
• Distance
• Shielding
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Injuries Associated with
Radiological Incidents
• Acute Radiation Syndrome (ARS)
• Localized radiation injuries/cutaneous radiation
syndrome
• Internal or external contamination
• Combined radiation injuries with
- Trauma
- Burns
• Fetal effects
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Acute Radiation Syndrome
A Spectrum of Disease
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Phases of Acute Radiation
Syndrome
Exposure
Prodromal
Stage
Latent
Stage
Manifest
Illness
Time (days to years)
www.bt.cdc.gov/radiation/arsphysicianfactsheet.asp
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Recovery
Stages of Acute Radiation
Syndrome
Stage 1: (50-150 rads)
• No symptoms or minimal viral
symptoms for up to 48 hours
• Spontaneous recovery usually occurs
• Sterility is a risk
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Stages of Acute Radiation
Syndrome
•
•
•
•
Stage 2: The Hematopoetic Syndrome (150400 rads)
Whole body exposure
Bone marrow suppression occurs with
loss of WBC and platelets
Infection and bleeding problems occur
LD 50 250-400 rads
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Stages of Acute Radiation
Syndrome
Stage 3: Severe Hematopoetic Syndrome
(150-400 rads)
• Life saving bone marrow transplantation
needed
• Care rationing during MCI will lower LD50
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Absolute Lymphocyte Count
• Measure every 4 - 6 hours initial 48
hours
• Normal: approx 2500 cells/ml
• > 1200: probably non-lethal
• 300 to 1200 cells/ml: significant
(hospitalize)
• < 300 cells/ml: critical
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Andrews Curve
1:
2:
3:
4:
1 Gy
4 Gy
6 Gy
7.1 Gy
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Stages of Acute Radiation
Syndrome
Stage 4: The Gastrointestinal Syndrome
(150-400 rads)
• GI lining cells die
• Severe diarrhea and electrolyte losses
• Life saving fluid and electrolyte
replacement
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Stages of Acute Radiation
Syndrome
Stage 5: The CNS Syndrome (>1500 rads)
• Confusion, ataxia, and sensory deficits
• Death within 48 hrs regardless of treatment
• Early appearance of CNS symptoms is an
ominous sign
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Pre-Hospital Management
• Evacuation of persons who are in the
path of a radiation cloud is the most
effective pre-hospital measure – this
action is the responsibility of public health
authorities
• Need effective communication with
residents as to steps they can take to
reduce exposure
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Patient Management - Priorities
• Initial triage and decontamination are ideally
done outside the hospital (have a plan in
place) to avoid contamination of the ED
• Patients exposed only to external EM
radiation (e.g. x-ray or gamma rays) are not
radioactive; patients exposed to particulate
radiation will be radioactive
• Standard medical triage is the highest priority
• Radiation exposure and contamination are
secondary considerations
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Patient Management - Protocol
Based on:
• Injuries
• Signs and symptoms
• Patient history
• Contamination survey
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Hospital Management
• Security
• Radiation Safety Officers/dosimeters,
GM
• 24-hour hotline (217) 785-0600
• Radiation Duty Officer @ Illinois Department
of Nuclear Safety
• Waste disposal
• Labeled, plastic bags
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Management
• Contaminated patient –
immediately isolated until
monitored & decontaminated
• Monitor EMS and ambulance
• ABC’s
• Cover all wounds
• Radiation burns are like sun
burns
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External Contamination
• Radioactive material (usually in the form
of dust particles) on the body surface
and/or clothing
• Radiation dose rate from contamination
is usually low, but while it remains on
the patient it will continue to expose the
patient and staff
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Patient Decontamination
• Remove and bag the patient’s clothing
and personal belongings (this typically
removes 80 - 90% of contamination)
• Handle foreign objects with care until
proven non-radioactive with survey meter
• Survey patient and collect samples
- Survey face, hands and feet
- Survey rest of body
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Protecting Staff from
Contamination
• Use standard precautions
• Survey hands and clothing
frequently
• Replace contaminated gloves
or clothing
• Keep the work area free of
contamination
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Examples of Radiation Skin
Burns
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Decontamination of Skin
• Use multiple gentle efforts
• Use soap & water
• Cut hair if necessary (do not shave)
• Promote sweating
• Use survey meter
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Cease Patient Decontamination
• When decontamination efforts produce no
significant reduction in contamination
• When the level of radiation of the
contaminated area is less than twice
background
• Before intact skin becomes abraded
Consider internal contamination
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Decontamination of Wounds
• Contaminated wounds:
– Irrigate and gently scrub with
surgical sponge
– Debride surgically only as needed
• Contaminated thermal burns:
– Gently rinse
– Changing dressings will remove additional
contamination
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Specific Therapy
Radionuclide
Therapeutic Approach
Tritium
Dilution (force fluids)
Iodine-125 or I-131
KI, or SSKI
Cesium-134 or cesium- 137
Prussian blue
Strontium-89, or 90
Decrease abs (antacids),
blockage (strontium lactate),
displacement (oral phosphate),
mobilization (ammonium
chloride)
Plutonium
Zinc or calcium (DTPA)
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Radioiodines and Thyroid
Cancer
Radioiodines concentrate
In the thyroid gland and
can increase the risk of
thyroid cancer
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You can reduce the radioiodine
thyroid dose by giving potassium
iodide
• Potassium Iodide (KI)
considerations
• Who should get KI?
• Useful at the beginning of an
exposure
• Only protects against thyroid
cancer
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Dosage (KI)
Age Group
Infants < 1 month
Dosage
16 mg
Children 1 month – 3 yrs 32 mg
Children 3–18 yrs
65 mg
Adults
130 mg
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Key Points
• Ionizing radiation includes:
– Electromagnetic radiation: X and gamma
– Particulate radiation: alpha, beta, neutrons
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Key Points
• Patient can be:
– Irradiated externally
– Contaminated with radionuclides
• Which patients are radioactive?
– Those contaminated with radionuclides
– These patients need to be decontaminated
– Some internally deposited radionuclides can be
removed with chelation therapy
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Key Points
• Protect yourself from radiation:
– Reduce the time of exposure
– Increase the distance from the radiation
source
– Apply shielding between yourself and the
radiation source
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Key Points
• Acute Radiation Syndrome:
– Stages progress from hematopoetic to gastrointestinal
to central nervous system with increasing dose
– The absolute lymphocyte count is the best predictor of
dose
• Long-term consequences
– Increase in cancer, especially thyroid cancer
– With radioiodine exposure, thyroid dose can be
reduced by using KI
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Key Points
• Have a radiation disaster management
plan in place for your hospital
• Be prepared for psychological
consequences
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Resources
• CDC Bioterrorism – www.bt.cdc.gov
• Radiation Emergency Assistance Center
& Training Site (REAC/TS) http://www.orau.gov/reacts/default.htm
• Medical management of radiological
casualties handbook www.afrri.usuhs.mil
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This completes the current
presentation.
Radiological Events
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