Meiosis and producing genetically diverse offspring Bonus #1 and #2 are posted CB 17.3 Protein CB 13.5 {Meiosis: producing gametes} For life to exist, the information (genes) must be passed on. {Mitosis: producing more cells} CB 12.4 Mitosis: A DNA Perspective Mitosis plays a role in: • Growth and Development • Repair and Turnover of Cells • Reproduction –Asexual CB 12.5 The Cell Cycle start of mitosis CB 12.6 CB 13.5 {Meiosis: producing gametes} For life to exist, the information (genes) must be passed on. {Mitosis: producing more cells} Asexaul Reproduction extremely low genetic diversity vs. Sexaul Reproduction greater genetic diversity How does sexual reproduction generate genetic diversity? Gene for growth hormone Gene for brown hair pigment G h QuickTime™ and a Graphics decompressor are needed to see this picture. e e n m e fo r ogl ob i n QuickTime™ and a Graphics decompressor are needed to see this picture. QuickTime™ and a Graphics decompressor are needed to see this picture. Gene for blue eye pigment G DN e n e A fo p r oly Haploid chromosomes m e r ase Allele for low express (short) Gene for growth hormone Allele for high express (tall) Allele for black hair Gene for hair color Allele for black hair Allele for sickle cell Hb Gene for hemoglobin Allele for normal Hb Diploid chromosomes Each pair of chromosomes is comprised of a paternal and maternal chromosome sister chromatids= replicated DNA (chromosomes) tetrad= pair of sister chromatids CB 13.4 CB 13.7 Meiosis splits apart the pairs of chromosomes. X 23 in humans haploid X 23 in humans X 23 in humans diploid X 23 in humans Inheritance = The interaction between genes inherited from Mom and Dad. Asexaul Reproduction extremely low genetic diversity vs. Sexaul Reproduction greater genetic diversity How does sexual reproduction generate genetic diversity? CB 13.7 Meiosis splits apart the pairs of chromosomes. X 23 in humans CB 13.11 Crossing-over (aka Recombination) DNA cut and religated DNA cut and religated CB 13.11 Crossing-over: Proteins in the cell cut and religate the DNA, increasing the genetic diversity in gametes. CB 13.10 Independent Assortment (aka Random Assortment) CB 13.10 Independent Assortment 2 possibilities for each pair, for 2 pairs 22 = 4 combinations CB 13.10 Independent Assortment 2 possibilities for each pair, for 23 pairs 223 = 8,388,608 combinations CB 13.9 Crossingover Meiosis: In humans, crossing-over and (Ind. Assort.) independent assortment lead to over 1 trillion possible unique gametes. (1,000,000,000,000) Meiosis I Meiosis II 4 Haploid cells, each unique Asexaul Reproduction extremely low genetic diversity vs. Sexaul Reproduction greater genetic diversity How does sexual reproduction generate genetic diversity?