Case Study - Katherine Kampen

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SG: Case Study

Lindsay Dvorak

Joel Fruchtnicht

Katie Kampen

Victoria Souhlas

Stephanie Spann

Background Information

- 72 y/o Male

- history of tobacco chewing and smoking

- Pt was admitted to the hospital in Meerut

India, on December 15, 2000

Symptoms

Pt reported:

Progressive hoarseness

loss of appetite

weight loss

difficulty in swallowing solid foods in the last 6 months

pain in the right ear and pain in the right side of the neck below the mandible in the last 4 months

pt was unable to swallow solid foods 15 days prior to admission

As soon as he ate solid food, he immediately vomited out with a coughing reflex (blood stained)

Upon admission..

- pt presented with:

- Significant difficulty in swallowing solid foods

- hoarseness of voice

- complaint of pain in the right ear and right side of neck below the mandible

- A physical examination revealed enlarged cervical lymph nodes on right side of neck

Signs and Symptoms Head and

Neck Cancer seen in SG

Change in voice (hoarse)

Difficulty swallowing; dysphagia

Enlarged cervical lymph nodes

Ear pain

Weight loss and loss of appetite

Vomiting with traces of blood

Other signs to check for include:

lump in the neck

a broadening of the larynx

tenderness in the neck

dyspnea- difficulty breathing

Referral

- After examination in the hospital a referral was made to the ENT for Laryngoscopic examination

Anatomical Signs

Pharyngoscopy and laryngoscopy are often used to check for signs of head and neck cancer

A physician (ENT) will perform the procedure to determine presence and to what extent of cancer is present

Severity and type identified by the

Tumor Classification System

Tumor Classification System

T- Tumor Size - T1 (smallest)- T4 (largest)

M- Presence or absence of Metastesis outside the region

N- Nodal Status- # of nodes thought to be involved with the tumor

Larynx is divided into 3 areas:

1. Supraglottis

2. Glottis

3. Subglottic

The extent of effects will depend on the site and size of the tumor

Suspected Anatomy of SG

Cancer is one of the diseases that may affect the anatomy and structures of the oral cavity, pharynx and larynx

If a malignant lesion affects one or both vocal folds directly, hoarseness will result due to invasion of the tumor on the structures

The magnitude will depend on the extent and site of the carcinoma

Observable Physiological Signs

Laryngoscopic examination may reveal anything from a small, well- defined tumor to a large and diffuse tumor involving any part of the larynx or vocal folds

As the severity of the lesion increases it becomes more invasive which negatively affect vibratory vocal fold behavior

Lesion can cause the vocal folds to become stiff which would affect the mucosal wave and amplitude of vibration

Measurable Physiological Signs

With large tumors, airflows are generally increased due to large leakage flows because the tumors can prevent vocal fold closure

Mean airflow rates can increase

Subglottal air pressures may be increased because of the increased stiffness of the vocal folds

Here’s why...

Cancerous lesions invade the tissue and destroy normally behaving cells

Invasion of the tumor into the various levels of the lamina propria and muscle results in greater stiffness of the tissue resulting in reduced horizontal excursion of the affected fold and often of the contralateral fold and restricted or absent mucosal wave

prevents vocal fold closure

A variety of benign and malignant tumors may be found in the laryngeal or neck region

Such tumors may obstruct the airway directly or may occupy space and place pressure on the trachea or larynx

Dysphagia

Depending on site and lesion, the obstruction of a tumor could result in oropharyngeal dysphagia

If the tumor is located near the vocal folds, it can impede on airway closure resulting in pharyngeal dysphagia

Respiratory System

The respiratory system would need to be assessed due to:

Increased risk for respiratory dysfunction and anatomical changes due to history of smoking and complaints of voice disorder

Enlarged lymph nodes can also be indicative of an

Upper Respiratory infection or cancer affecting the lungs and/or respiratory system

Effects of Smoking Tobacco on

Respiratory System

Irritation of the trachea and larynx

reduced lung function and breathlessness due to swelling and narrowing of lung airways

impairment of lungs’ clearing system resulting in lung irritation and damage

increased risk of lung infection and symptoms such as coughing and wheezing

permanent damage to air sacs of the lungs

can cause cancer of the lungs, esophagus, larynx, mouth, throat and more

Lymphadenopathy

Enlarged Lymph nodes

Lymph nodes filter the lymphatic fluids on its way to central venous circulation, removing cells and other materials

Pathogenic microorganisms carried in the lymphatic fluid can directly infect the lymph nodes

Because lymph nodes participate in the bodys’ immune response, a large number of infectious and inflammatory disorders and cancers are potential causes

Leading causes of enlarged lymph nodes include:

Idiopathetic, self limited (no known cause)

Upper Respiratory Infection

Cancer (lung, gastrointestional, retropertineal)

Lymphatic Drainage System

How much of normal tissue resected in a head and neck cancer patient is determined by the site of malignancy

The lymphatic drainage system is a series of vessels that drain fluid from cells

Depending on the way the system drains, it could determine the way in which the tumor spreads

For example, because of the way the lymphatic system drains in the supraglottic larynx, a tumor in that area will not spread downward to the

TVF and/or subglottic larynx unless the tumor is at the base of the epiglottis

So it is important to note where and to what extent a tumor has spread to in order to see what changes can be expected anatomically

Following ENT consult...

-MBSS to assess anatomy and physiology of swallowing

-Assess respiratory patterns

-Assess voice production

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